Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_CANONICAL NF-KAPPAB PATHWAY |
| Enrichment Score (ES) | -0.72929907 |
| Normalized Enrichment Score (NES) | -1.5145934 |
| Nominal p-value | 0.002444988 |
| FDR q-value | 0.34452006 |
| FWER p-Value | 0.985 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ARRB2 | 2060441 | 1293 | 0.658 | -0.0215 | No | ||
| 2 | NFKB1 | 5420358 | 1928 | 0.422 | -0.0248 | No | ||
| 3 | BCL3 | 3990440 | 3203 | 0.139 | -0.0832 | No | ||
| 4 | PRKCA | 6400551 | 3576 | 0.103 | -0.0957 | No | ||
| 5 | PIK3R1 | 4730671 | 7321 | 0.013 | -0.2963 | No | ||
| 6 | REL | 360707 | 8673 | 0.007 | -0.3685 | No | ||
| 7 | RAN | 2260446 4590647 | 9367 | 0.004 | -0.4055 | No | ||
| 8 | XPO1 | 540707 | 9449 | 0.004 | -0.4095 | No | ||
| 9 | ATM | 3610110 4050524 | 10891 | 0.000 | -0.4871 | No | ||
| 10 | TNF | 6650603 | 12391 | -0.005 | -0.5674 | No | ||
| 11 | FBXW11 | 6450632 | 13100 | -0.009 | -0.6048 | No | ||
| 12 | SRC | 580132 | 13235 | -0.010 | -0.6113 | No | ||
| 13 | SYK | 6940133 | 13689 | -0.014 | -0.6347 | No | ||
| 14 | PIK3CA | 6220129 | 13861 | -0.016 | -0.6427 | No | ||
| 15 | ERC1 | 1580170 2630717 6110762 6840280 | 14397 | -0.028 | -0.6694 | No | ||
| 16 | NOD2 | 2510050 | 14872 | -0.050 | -0.6912 | No | ||
| 17 | MALT1 | 4670292 | 14919 | -0.053 | -0.6898 | No | ||
| 18 | RELB | 1400048 | 15248 | -0.075 | -0.7020 | No | ||
| 19 | IKBKG | 3450092 3840377 6590592 | 15397 | -0.091 | -0.7034 | No | ||
| 20 | BIRC2 | 2940435 4730020 | 15427 | -0.093 | -0.6981 | No | ||
| 21 | NFKB2 | 2320670 | 15588 | -0.110 | -0.6987 | No | ||
| 22 | UBE2D3 | 3190452 | 15912 | -0.149 | -0.7051 | No | ||
| 23 | RIPK2 | 5050072 6290632 | 16153 | -0.187 | -0.7044 | No | ||
| 24 | IKBKB | 6840072 | 16617 | -0.298 | -0.7075 | Yes | ||
| 25 | LCK | 3360142 | 16671 | -0.311 | -0.6876 | Yes | ||
| 26 | RELA | 3830075 | 16834 | -0.358 | -0.6701 | Yes | ||
| 27 | CYLD | 6590079 | 17073 | -0.438 | -0.6510 | Yes | ||
| 28 | CHUK | 7050736 | 17374 | -0.567 | -0.6256 | Yes | ||
| 29 | TRAF6 | 4810292 6200132 | 17407 | -0.581 | -0.5849 | Yes | ||
| 30 | MAPK14 | 5290731 | 17410 | -0.583 | -0.5424 | Yes | ||
| 31 | NFKBIA | 1570152 | 17455 | -0.610 | -0.5002 | Yes | ||
| 32 | BCL10 | 2360397 | 17734 | -0.764 | -0.4593 | Yes | ||
| 33 | MAP3K14 | 5890435 | 17867 | -0.866 | -0.4031 | Yes | ||
| 34 | TNFAIP3 | 2900142 | 18460 | -1.987 | -0.2898 | Yes | ||
| 35 | TNFRSF1A | 1090390 6520735 | 18609 | -4.080 | 0.0004 | Yes |
